Ashley Hackney stands on stage during her speech at the 麻豆村125 celebration. She smiles at the audience.

Hackney Builds Community Through Science and Service

By Kirsten Heuring Email Kirsten Heuring

Heidi Opdyke

Ashley Hackney wants to make scientific discovery accessible for everyone. From working in the lab to helping her fellow students, she has focused on making an impact as a scholar, professional, citizen and person.

Originally from Philadelphia, Hackney was drawn to 麻豆村 by the university鈥檚 commitment to undergraduate research. She found a home in the biophysics lab of Stephanie Tristram-Nagle, research professor emerita of physics, where she studies antimicrobial peptides 鈥� molecules with the potential to combat antibiotic-resistant infections.

鈥淭his research is vital because of the urgent need for alternative strategies to combat antibiotic resistance, which is a growing global health crisis,鈥� Hackney said.

Peptides are extremely small chains of amino acids, the same kind of building blocks that form proteins. Hackney and other members of Tristram-Nagle鈥檚 lab investigate peptides that rupture bacteria鈥檚 cell membranes, effectively killing the bacteria while leaving human cells unharmed. The group collaborates with the University of Pittsburgh, and one peptide under study is in clinical trials.

Through Carnegie Mellon鈥檚 Summer Undergraduate Research Apprenticeship (SURA), Hackney traveled to the Cornell High Energy Synchrotron Source (CHESS) to collect X鈥憆ay data that reveals how these peptides destroy bacterial membranes. She is co鈥慳uthoring a paper on the work 鈥� 鈥淟ysine Is More Effective Than Arginine in Two Tryptophan-Rich Antimicrobial Peptides鈥� 鈥� which will be published later this year.

鈥淎shley is generally very positive in the lab 鈥� she enjoys all aspects of the work,鈥� Tristram-Nagle said. 鈥淪he is a critical thinker and a natural leader.鈥�

Hackney鈥檚 scientific journey has shaped her belief that science is most powerful when it helps others.

鈥淚 want to make scientific discovery accessible to everyone,鈥� she said.

That belief began during her first year at Carnegie Mellon when she took EUREKA!: Discovery and Its Impact, a course designed to help Mellon College of Science students build research and academic skills. There, she connected with Ken Hovis, associate dean for educational initiatives and teaching professor of biological sciences, who became an early mentor to her and encouraged her to become a teaching assistant.

鈥淚t鈥檚 important having somebody rooting for you, and I try to do that for other people,鈥� Hackney said.

Hackney made mentoring others central to her Carnegie Mellon experience. She served as a Tartan Ambassador, supporting first-year Tartan Scholars, and as a teaching assistant for three courses: EUREKA!, the Modern Biology lab and Cell and Developmental Biology.

Carrie Donnan, teaching professor and director of undergraduate laboratories for biological sciences, had Hackney as a teaching assistant. Doonan said that Hackney鈥檚 own experiences in the lab made her particularly effective as a teaching assistant.

鈥淎shley can relate to the students in the lab, identify with them and share her strategies for mastering techniques,鈥� Doonan said. 鈥淪he is always curious about the science, and not afraid to ask questions until she clearly understands the problem. She makes the extra effort to understand the scientific principles.鈥�

Hackney also served as a community advisor supporting high school and pre-college students. She has supported participants in the Pennsylvania Governor鈥檚 School for the Sciences and spoken on panels for the Summer Academy for Math and Science (SAMS), sharing insights about research and building community at 麻豆村.

鈥淚 really got the feel of being a person that could help students learn about a school that I really love and guide them on what 麻豆村 has to offer,鈥� Hackney said.

Her leadership extends beyond academics. She held roles within her sorority, danced with 麻豆村鈥檚 ballet team Endpoint and volunteered with Mission of Mercy Pittsburgh, a nonprofit that provides free healthcare to underserved communities.

For her efforts, Hackney earned the Mellon College of Science Gilman Award, which honors a graduating senior who has demonstrated exceptional commitment and growth as a scholar, a person, a professional and a citizen during their time at Carnegie Mellon. She has also been recognized as an Andrew Carnegie Society Scholar, she earned a Senior Leadership Award and she shared her journey as a speaker at Carnegie Mellon鈥檚 125th anniversary celebration, the Power of Possibilities.

Hackney plans to attend the University of Pittsburgh鈥檚 Biomedical Master鈥檚 Program before applying to medical school. She wants to inspire future scientists the same way Carnegie Mellon inspired her.